A Research article is a primary source – it reports the methods and results of an original study performed by the authors (see Research articles below).
A Review article is a secondary source – it provides a synthesis, perspective, and overview of the existing literature on a topic (see Review Articles).
2022
- The pleiotropic benefits of statins include the ability to reduce CD47 and amplify the effect of pro-efferocytic therapies in atherosclerosis. Nature Cardiovascular Research. Kai-Uwe Jarr, Jianqin Ye, Yoko Kojima, Zhongde Ye, Hua Gao, Sofie Schmid, Lingfeng Luo, Richard A. Baylis, Mozhgan Lotfi, Nicolas Lopez, Anne V. Eberhard, Bryan Ronain Smith, Irving L. Weissman, Lars Maegdefessel, and Nicholas J. Leeper. PDF Link
2021
- Macrophage-targeted singled walled carbon nanotubes stimulate phagocytosis via pH-dependent drug release. Nano Research. Y. Zhang, J. Ye, N. Hosseini-Nassab, A. Flores, I. Kalashnikova, S.L. Paluri, M. Lotfi, N.J. Leeper, B.R. Smith* (2021).14, 762-769. PDF Link
- Ultraselective Carbon Nanotubes for Photoacoustic Imaging of Inflamed Atherosclerotic Plaques. Gifani, M., Eddins, D. J., Kosuge, H., Zhang, Y., Paluri, S. L. A., Larson, T., Leeper, N., Herzenberg, L. A., Gambhir, S. S., McConnell, M. V., Ghosn, E. E. B.R. Smith Adv. Funct. Mater. (2021.) 2101005. PDF Link
2020
- 18-FDG-PET imaging detects plaque vulnerability and response to therapeutic intervention in a murine model of advanced atherosclerotic disease. Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB). K. Uwe-Jarr, J. Ye, Y. Kojima, V. Nanda, A.M. Flores, P. Tsantilas, Y. Wang, N. Hosseini-Nassab, A.V. Eberhard, M. Lotfi, M. Kaller, B.R. Smith, L. Maegdefessel, N.J. Leeper (2020). 40(12) 2821-2828. PDF Link
- Reduction Triggered In Situ Polymerization in Living Mice. Journal of the American Chemical Society (JACS). L. Cui, S. Vivona, B.R. Smith, S. Kothapalli, J. Liu, X. Ma, Z. Chen, M. Taylor, P.H. Kierstead, J.M.J. Frechet, S.S. Gambhir, J. Rao (2020). 142(36) 15575-15584. PDF Link
- Particle tracking microrheology of cancer cells in living subjects. Materials Today. P-H, Wu^, S.S. Gambhir^, C. Hale, W-C Chen, D. Wirtz^, B.R. Smith^ (2020). Particle tracking microrheology of cancer cells in living subjects. Materials Today. 39, 98-109. ^Corresponding author. Highlighted in: Science Daily | Phys.org PDF Link
- Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis. Nature Nanotechnology. A. Flores, N. Hosseini-Nassab, K-U, Jarr, J. Ye, X. Zhu, R. Wirka, A.L. Koh, P. Tsantilas, Y. Wang, V. Nanda, Y. Kojima, Y. Zeng, M. Lotfi, R. Sinclair, I.L. Weissman, E. Ingelsson, B.R. Smith*, N. Leeper* (2020). 15(2) 154-161. *Equal and Co-Corresponding authors. [Cover article] Highlighted in: Detroit News | Google News | Paul W. Smith Detroit Radio Show PDF Link
- Nanoparticles decorated with granulocyte-colony stimulating factor for targeting myeloid cells. Nanoscale. K. Margulis, A. Honkala, I. Kalashnikova, S.E. Noll, M. Hill, R.N. Zare*, B.R. Smith* (2020). 12(4) 2752-2763. *Corresponding author PDF Link
2019
- Quantitative Drug Release Monitoring in Tumors of Living Subjects by Magnetic Particle Imaging Nanocomposite. Nano Letters. X. Zhu, J. Li, P. Peng, N. Hosseini-Nassab, B.R. Smith* (2019). 19(10) 6725-6733. *Corresponding author PDF Link
2018
- Extravasation of Brownian Spheroidal Nanoparticles through Vascular Pores. Biophysical Journal. P. Shah, T. Y. Lin, B.R. Smith*, E.S.G. Shaqfeh* (2018). 115(6), 1103-1115. *Co-corresponding authorship [Cover article]. Highlighted in: Stanford Engineering Magazine. Myers, A. New computer model designs a drug delivery strategy to fight cancer. PDF Link
2015
- Predictive Modeling of Drug Response in Non-Hodgkin’s Lymphoma. PLoS ONE. H. Frieboes*, B.R. Smith*, Z. Wang*, M. Kotsuma, K. Ito, A. Day, M. Loewenberg, B. Cahill, C. Flinders, S. Mumenthaler, P. Mallick, S.S. Gambhir, V Cristini. (2015). 10(6): e0129433. *Co-first authorship. PDF Link
2014
- Selective Uptake of Single-walled Carbon Nanotubes by Circulating Monocytes for Enhanced Tumour Delivery. Nature Nanotechnology. 9(6), 481-487. B.R. Smith^, E. Ghosn, H. Rallapalli, J. Prescher, L. Herzenberg, S.S. Gambhir^ (2014). 9(6), 481-487. ^Corresponding author. Highlighted in: Stephan, M. Carbon Nanotubes Are Picky Hitchhikers (2014). PDF Link
- Researchers elucidate the uptake mechanism of single-walled carbon nanotubes (2014). NANOMEDICINE. Science Translational Medicine. 6 (234) (Editor’s Choice) | Coaker, H. Vol: 9, Issue: 8. p. 1126. | Feature. Ten years in images. Nature Nanotechnology. 2016. 11, 836-840. | Blogs and other New Articles
2013
- High-resolution, serial intravital microscopic imaging of nanoparticle delivery and targeting in a small animal tumor model. Nano Today [#2 ranked journal in Nanotechnology], B.R. Smith^, C. Zavaleta, Z. Liu, R. Tong, J. Ramunas, H. Dai, S.S. Gambhir^ (2013). 8(2) 126-137. ^Corresponding author. PDF Link
- An Integrated Computational/Experimental Model of Lymphoma Growth. PLoS Computational Biology. H. Frieboes, B.R. Smith, Y-L Chuang, K. Ito, A.M. Roettgers, S.S. Gambhir, V. Cristini (2013). 9(3): e1003008. PDF Link
2012
- Unexpected dissemination patterns in lymphoma progression revealed by serial imaging within a murine lymph node. Cancer Research. K. Ito*, B.R. Smith*, N. Parashurama, J-K, Yoon, S.Y. Song, C. Miething, P. Mallick, S. Lowe, S.S. Gambhir (2012).72, 6111-6118. *Co-first authorship. PDF Link
- Remodeling of Endogenous Mammary Epithelium by Breast Cancer Stem Cells. Stem Cells. N. Parashurama, N. Lobo, K. Ito, A. Mosely, F. Habte, B.R. Smith, J. Lam, I. Weissman, M.F. Clarke, S.S. Gambhir (2012). 30(10), 2114-2127. [Cover article]. PDF Link
- Non-destructive, serial in vivo imaging of a tissue-flap using a tissue adhesion barrier: applications for IVM imaging in the mammary fat pad and lymph node. M. Kotsuma*, N. Parashurama*, B.R. Smith, K. Ito, S.S. Gambhir (2012). 1(1), 1-8. IntraVital. [Cover article]. PDF Link
- Fluorescent Magnetic Nanoparticles for Magnetically Enhanced Cancer Imaging and Targeting in Living Subjects. ACS Nano. A. Fu, R.J. Wilson, B.R. Smith, J. Wright, C. Earhart, B. Bales, S. Guccione, S.X. Wang, S.S. Gambhir (2012). 6(8), 6862-6869. PDF Link
- Shape Matters: Intravital Microscopy Reveals Surprising Geometrical Dependence for Nanoparticles in Tumor Models of Extravasation. Nano Letters. B.R. Smith, P. Kempen, D. Bouley, A. Xu, Z. Liu, N. Melosh, H. Dai, R. Sinclair, S.S. Gambhir (2012). 12(7), 3369-77. PDF Link
2011
- Correlative Microscopy of Tumor Vasculature. Microscopy and Microanalysis. P. Kempen, B.R. Smith, M. Kircher, S.S. Gambhir, R. Sinclair (2011). 17 (Supp S2), 360-361. PDF Link
2010
- Dynamic Visualization of RGD-quantum dot Binding to Tumor Neovasculature and Extravasation in Multiple Living Mouse Models using Intravital Microscopy. B.R. Smith, Z. Cheng, A. De, J. Rosenberg, S.S. Gambhir (2010). Small. 6(20), 2222-2229. FEATURED ON: Frontispiece PDF Link
- A Comparison between Time Domain and Spectral Imaging Systems for Imaging Quantum Dots in Small Living Animals. Molecular Imaging and Biology. A. de la Zerda, M.L. Schipper, S. Keren, S. Bodapati, B.R. Smith, J.S.T. Ng, S.S. Gambhir (2010). 12(5), 500-508. PDF Link
- Assessing delivery and quantifying efficacy of small interfering ribonucleic acid therapeutics in the skin using a dual-axis confocal microscope. Journal of Biomedical Optics Letters. H. Ra, E. Gonzalez, B.R. Smith, S.S. Gambhir, G.S. Kino, O. Solgaard, R.L. Kaspar, C. Contag (2010). 15(3): 036027. PDF Link
2009
- Multiplexed imaging of surface enhanced Raman scattering nanotags in living mice using noninvasive Raman spectroscopy. Proceedings of the National Academy of Sciences. C. Zavaleta, B.R. Smith, I. Walton, W. Doering, G. Davis, B. Shojaei, M.J. Natan, S.S. Gambhir (2009). 106 (32), 13511-13516. PDF Link
- Functional and Transcriptional Characterization of Human Embryonic Stem-Cell-Derived Endothelial Cells for Treatment of Myocardial Infarction. PLoS ONE. Z. Li, K.D. Wilson, B.R. Smith, D. Kraft, F. Jia, X. Xie, M. Huang, G. Hoyt, P. Chu, R.C. Robbins, I.L. Weissman, S.S. Gambhir, J.C. Wu (2009). 4(12), 1-13. PDF Link
- Real-time visualization of RGD-quantum dot binding in tumor neovasculature using intravital microscopy in multiple living mouse models. Proceedings of SPIE. B.R. Smith, Z. Cheng, A. De, A.L. Koh, R. Sinclair, S.S. Gambhir (2009). Volume 7189, pp. 718915-718915-12.
- Photoacoustic Molecular Imaging using Single Walled Carbon Nanotubes in Living Mice. Proceedings of SPIE. A. de la Zerda, C. Zavaleta, S. Keren, S. Vaithilingam, S.Bodapati, R. Teed, Z. Liu, J. Levi, B.R. Smith, T-J, Ma, O. Oralkan, Z. Cheng, X. Chen, H. Dai, B.T. Khuri-Yakub, S.S. Gambhir (2009). Volume 7177, pp. 717725-717725-12. PDF Link
2008
- Endothelial Differentiation of Human Embryonic Stem Cell and Functional Blood Vessels Formation In Vivo. Blood. Z. Li, B.R. Smith, M. Huang, X. Xie, S.S. Gambhir, J.C. Wu (2008). 112(11), 5455.
- Carbon Nanotubes as Photoacoustic Molecular Imaging Agents in Living Mice. Nature Nanotechnology. A. de la Zerda , C. Zavaleta, S. Keren, S. Vaithilingam, S. Bodapati, Z. Liu, J. Levi, B.R. Smith, T. Ma, O. Oralkan, Z. Cheng, X. Chen, H. Dai, B.T. Khuri-Yakub, S.S. Gambhir (2008). 3, 557-562.
- Real-time Intravital Imaging of RGD-Quantum Dot binding to Luminal Endothelium in Mouse Tumor Neovasculature. Nano Letters. B.R. Smith, Z. Cheng, A. De, A.L. Koh, R. Sinclair, S.S. Gambhir (2008). Sept; 8(9): 2599-2606. [Cover Article] PDF Link
2007
- Imaging of Atherosclerotic Plaques by Molecularly Targeted Nanoparticulates (USPIOs): Proof-of-Principle with MRI. Biomedical Microdevices. B.R. Smith, J. Heverhagen, M.V. Knopp, P. Schmalbrock, J. Shapiro, M. Shiomi, N.I. Moldovan, M. Ferrari, S.C. Lee (2007). 9:5, 719-727. PDF Link
2005
- The Molecular Analysis of Breast Cancer Utilizing Targeted Nanoparticulates (USPIOs): Proof-of-Principle with Ultrasound. Technology in Cancer and Research Treatment. J. Sakamoto, B.R. Smith, B. Xie, S. Rokhlin, S.C. Lee, M. Ferrari (2005). 4:6, 627-636. PDF Link
- Biologically-Targeted Super-paramagnetic Nanoparticulates to Atheromatous Plaque. Molecular Imaging. B.R. Smith, J. Heverhagen, M.V. Knopp, S.C. Lee (2005). 4:3, 312.
2002
- Osmotic Pressures for Binary Solutions of Non-electrolytes. Biomedical Microdevices. V.T. Granik, B.R. Smith, S.C. Lee, M. Ferrari (2002). 4:4, 309-321. PDF Link
