Principal Investigator

Dr. Bryan Smith

517.353.7073
smit2901 at msu.edu

TITLE
  • Associate Professor of Biomedical Engineering within the Engineering School
  • Member of the Institute for Quantitative Health Science and Engineering
EDUCATION/BACKGROUND
  • Tufts University (degrees in Physics, Mathematics, and Biomedical Engineering)
  • The Ohio State University (PhD in Biomedical Engineering, minor in Physics)
  • Stanford University (Post-doc and then first independent faculty position in the Department of Radiology)
LAB FOCUS
  • Blending engineering, chemistry, biology, physics, and medicine to develop new imaging and therapeutic approaches
  • Developing novel nanotechnology-based strategies to harness the power of the immune system
  • Creating novel diagnostic imaging and therapeutic agents for diseases including cancer, atherosclerosis, and neurodegeneration
HOBBIES
  • Tennis, hiking, and skiing
  • Spending time with my family
AWARDS
  • K99/R00 Transition to Independence Award
  • AACR-Breast Research Foundation Career-Development Award for Translational Breast Cancer Research (2017)
  • AHA Transformational Project Award (2018)
  • Lilly Fellowship (directed toward leadership and education)

Administration & Support

Elizabeth Gill – Administrative Assistant

650.521.6237
gilleli1 at msu.edu

BACKGROUND
  • Small business life insurance sales and service
  • Administrative Support – served as Executive Assistant to the Chair of Radiology/Director of the Molecular Imaging Program at Stanford University (MIPS).
WORK/LAB INTERESTS
  • Enjoys the opportunity to make a difference in the lives of those with whom she interacts with every day.
  • Thoroughly enjoys learning about different aspects of scientific research and its relevant progress.
HOBBIES
  • Extensive reading, walking in nature
  • The professional arts including opera, theater, and the symphony
  • Spending time with family

Scott Hubbard – Volunteer Lab Support

shubbard at affiliate.msu.edu

EDUCATION/BACKGROUND
  • Bachelor of Science in Engineering Operations – Iowa State University
  • Technical writing and project management
  • User interface design/usability
WORK/LAB INTERESTS
  • Website administrator
  • Twitter content provider/administrator
  • Lab standard operating procedure (SOP) support
  • Other lab support activities (templates and documentation storage/organization, etc.)
HOBBIES
  • Like a dog, I love to chase after balls (pickleball, tennis, racquetball, and basketball)
  • Watching documentaries and sports of all kinds
  • Spending time with family and grandchildren

Post-Doctoral Researchers

Manisha Kumari

kumarima at msu.edu

EDUCATION/BACKGROUND
  • Bachelors: Science in Zoology, Botany, and Chemistry from Maharshi Dayanand University, India (2006)
  • Masters: Science in Biotechnology from Kurukshetra University, India (2008)
  • Ph.D: Science from Academy of Scientific and Innovative Research and CSIR-IGIB, India (2018)
  • Google Scholar Profile
  • Curriculum Vitae (CV)
RESEARCH FOCUS/LAB INTERESTS
  • Joined lab in June 2022
  • Interested in developing nano-immunotherapeutic and nano-immunoimaging platforms for cancer and other biomedical applications
  • Interested in developing a combination of nanoparticle-mediated chemo- and immuno-therapy to improve the overall therapeutic outcome
  • Past work focused on developing nanoparticle-mediated drug delivery systems for cancer therapeutics, and on developing non-invasive assay for prostate cancer detection
HOBBIES
  • Reading and spending time with family
AWARDS
  • Junior Research Fellowship from CSIR, India (2012) upon qualifying National Eligibility Test (NET) with 34th All India Rank
  • Senior Research Fellowship from CSIR, India (2014)

Romila Manchanda

manchan7 at msu.edu

 

 

 

EDUCATION/BACKGROUND
  • Bachelors: Science in Chemistry from University of Delhi, India (1995); Science in Chemistry from University of Delhi, India (1998)
  • Ph.D: Chemistry from C.C Singh University and IGIB, India (2007)
  • Google Scholar Profile
  • Curriculum Vitae (CV)
RESEARCH FOCUS/LAB INTERESTS
  • Joined lab on March 16, 2020
  • Interested in design/fabrication and engineering of novel biodegradable polymeric nanoimmunotherapic systems for various cancer treatments
  • Hopes to improve clinical outcomes of people with cancer through improved cancer therapies
  • Past work focused on developing controlled release delivery systems to increase payload release rates and designing bio-conjugated nanoparticles for targeted therapy in cancer treatment
HOBBIES
  • Cooking, learning astrology
AWARDS
  • Young Scientist Project from Department of Science and Technology (SERC Fast Track Proposals for Young Scientists Scheme), Government of India (2007)
  • “Novel polymeric nanoparticles for drug delivery application” NIH R15 grant (2013)

Madhu Puri

Purimadh at msu.edu

EDUCATION/BACKGROUND
  • Bachelors: Science in Biotechnology, Zoology and Chemistry from Panjab University, Chandigarh, India (2008)
  • Masters: Science in Human Genomes from Panjab University, Chandigarh, India (2010)
  • Ph.D: Medical Microbiology from Justus Liebig University, Giessen, Germany (2014)
  • Curriculum Vitae (CV)
RESEARCH FOCUS/LAB INTERESTS
  • Joined lab in September 2022
  • Develop novel nano-immunotherapeutic and nano-immunodiagnostic strategies for cancer and atherosclerosis and improve on existing methods
  • Past work focused on understanding…
    • the molecular mechanisms of host-pathogen interactions during bacterial and parasitic infections (primarily autophagy, arginine sensing and epigenetic modulations)
    • the role of host immune response in the defense against infectious diseases and the mechanisms of immune evasion employed by these pathogens to establish infection
HOBBIES
  • Reading & traveling
  • Spending time with family
  • Working out
AWARDS
  • UGC-D.S. Kothari Post-Doctoral Fellowship (higher fellowship awarded for outstanding candidate recognition), University Grants Commission, India (2019)
  • Graduate fellowship by the Bundesministerium für Bildung und Forschung and LOEWE, German Government, Germany (2010-2014)

Swati Sharma

shar1145 at msu.edu

EDUCATION/BACKGROUND
  • Bachelors: Zoology (Honors), University of Delhi, New Delhi, India (2010) 
  • Masters: Zoology, University of Delhi, New Delhi, India (2012) 
  • Ph.D: Biological Sciences, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India (2022)
  • Curriculum Vitae (CV)
RESEARCH FOCUS/LAB INTERESTS
  • Joined the laboratory in Oct 2022 
  • Understanding the mechanistic insights of myeloid derived cells in uptake and processing of nanoparticle conjugated drugs in animal models of atherosclerosis and cancer/ cancer immunotherapy.
  • Understanding the potential role of combining nanoparticle drug delivery system with CAR-T cell therapy to reduce on-target off tumor effects in solid tumors.
HOBBIES
  • Reading, writing and cooking 
  • Exploring nature trails and outdoor activities
AWARDS
  • Qualified for the CSIR-Junior Research Fellowship – December 2013, CSIR-UGC Joint NET (National Eligibility Test), India. All India Rank-44 
  • Secured Lectureship – June 2013, CSIR-UGC Joint NET, India. All India Rank-36 
  • PhD-in training member, International Travel Grant Scholarship to attend the 2015 AAAAI Meeting, Houston, Texas, USA.

Darren Story

storydar at msu.edu

 

 

 

 

EDUCATION/BACKGROUND
  • Masters: Arts in English Language and Literature from Central Michigan University (2009); Science in Neuroscience from Central Michigan University (2017)
  • Ph.D: Applied Experimental Psychology from Central Michigan University (2020)
  • Curriculum Vitae (CV)
RESEARCH FOCUS/LAB INTERESTS
  • Joined lab in 2021
  • Current research focuses on role of inflammation in perivascular adipose tissue on hypertension
  • Past work has included use of stem cell therapies in neurodegenerative diseases (Huntington’s disease and Alzheimer’s disease) and characterization of animal models of neurodegenerative disease
HOBBIES
  • Reading, cooking
  • Video games, mountain biking
AWARDS
  • Dell Postdoctoral Collaboration Fellowship (2021)
  • James and Catherine Steinmetz Graduate Scholarship (2017 and 2018)

Yapei Zhang

zhangyap at msu.edu

EDUCATION/BACKGROUND
RESEARCH FOCUS/LAB INTERESTS
  • Joined lab in September 2019
  • Currently researching drug release monitoring in vitro/vivo using MPI
  • Mainly interested in utilizing Medical Imaging Modalities (CT, IVIS, MPI, MSOT, MP, etc.) to monitor drug release and the distribution of nanoparticles in vivo
  • Hopes to contribute to improving society for the better, especially regarding cancer treatment
HOBBIES
  • Painting, designing
  • Working out, traveling
AWARDS
  • Ph.D Primary/Secondary Scholarship (2015)
  • He Binglin Scholarship (2018), Graduate Secondary Scholarship (2018)

Graduate (Ph.D) Students

Alireza Aminoroaya-Yamini

aminoroa at msu.edu

EDUCATION/BACKGROUND
  • Bachelors: Chemical Engineering, Isfahan University of Technology, Iran (2017)
  • Masters: Polymer Engineering, Isfahan University of Technology, Iran (2020)
  • Ph.D: Pursuing doctorate of Chemical Engineering at MSU (2022-present)
  • Curriculum Vitae (CV)
RESEARCH FOCUS/LAB INTERESTS
  • Joined lab in Fall 2022
  • Current research focuses on developing nano-immunotherapeutic and nano-immunoimaging platforms for cancer therapy
  • Interested in Biomaterials, drug delivery, and gene delivery
HOBBIES
  • Reading books
  • Hiking, gym, and soccer
  • Spending time with family and friends

Yunxiu Qiu

yxqiu at msu.edu

EDUCATION/BACKGROUND
  • Bachelors: Materials Science and Engineering, Beihang University, China (2019)
  • Masters: Materials Science and Engineering, Washington University in St. Louis (2021)
  • Ph.D: Pursuing doctorate in ChEMS (Chemical Engineering and Materials Science) at MSU (2021-present)
  • Curriculum Vitae (CV)
RESEARCH FOCUS/LAB INTERESTS
  • Joined lab in 2021
  • Current research focuses on magnetic particle imaging (MPI) and mechanics of microfluids
  • Past work has included thermo-sensitive injectable hydrogels and their self-adhesive applications
HOBBIES
  • Cooking, playing video games
  • Planting flowers and vegetables

Medical Students

Zak Skelton

Skeltonz at msu.edu

EDUCATION/BACKGROUND
  • Bachelors: Kinesiology, Michigan State University (2019)
  • Doctor of Osteopathic Medicine (D.O.): Currently working on D.O. at MSU with an interest in pursuing surgery.
  • Curriculum Vitae (CV)
RESEARCH FOCUS/LAB INTERESTS
  • Joined lab in 2021
  • Current research focuses on the role of inflammation in perivascular adipose tissue on hypertension
  • Past research in exercise physiology testing on college athletes
HOBBIES
  • Video games and soccer
  • Cooking
AWARDS
  • Recipient of the 2019 Kinesiology Outstanding Senior Award
  • Nominee for the 2019 American Kinesiology Association Undergraduate Scholar Award
  • Recipient of 2017-2019 Lentz Memorial Scholarship

Undergraduate Assistants

Leo Barrios

586.488.8646
barriosl at msu.edu

YEAR/MAJOR
  • Sophomore planning to graduate in 2024
  • Genetics major
LAB INFORMATION/ASPIRATIONS
  • Joined lab in September 2020
  • Hopes to experience what it’s like to work in a lab setting and to explore his career options
MAIN CONTRIBUTIONS
  • Creation of the T-NIE Lab website
HOBBIES
  • Playing video games with friends

Kaylee Park

parkkayl at msu.edu

YEAR/MAJOR
  • Sophomore planning to graduate in 2023
  • Biochemistry and Molecular Biology major
LAB INFORMATION/ASPIRATIONS
  • Joined lab in September 2020
  • Hopes to expand knowledge on immunology and research in general
  • Currently exploring her career paths in pharmacology and veterinary medicine
MAIN CONTRIBUTIONS
  • Creation of the T-NIE Lab website
HOBBIES
  • Dancing, drawing
  • Graphic design, listening to music

See Past Members